Test Ηbsαg Combo Rapid Τest(Hepatitis Β)
The Anti-HBs (HBsAb) Test is a rapid chromatographic immunoassay for the qualitative detection of hepatitis B virus antibodies in human blood / serum / plasma.
The anti-HBs test uses solid-phase immuno-chromatographic technology for the qualitative detection of antibodies against hepatitis B in human blood / serum / plasma. The test is two sites in which the combination of polyclonal antibodies and recombinant HBs antigens are used to selectively detect antibodies against HBs antigens with a high degree of sensitivity. Recombinant HBs antigens are immobilized in the "T" test region and anti-HBsAg from goat polyclonal antibodies are immobilized in the "C" control region of the membrane.
Recombinant HBs conjugates coupled to colloidal gold particles have been dried on a conjugate surface.
The sample is inserted from the sample holder. If anti-HBs are present in the sample, anti-HBs bind to mobile recombinant HBsAg coupled to colloidal gold particles. Together they move towards the "T" test area. This complex moves further into the membrane in the T test region where it is immobilized by the specifically recombinant antigens coated on the membrane and causing the formation of a colored line, which confirms a positive result. The absence of this colored line indicates a negative result.
The unreacted conjugate as well as the immobilized clone, if any, are moved further and then immobilized by the antibodies coated in the control region C, creating a colored line. This control line serves to confirm the performance of the reagent and the analysis.
What Is Hepatitis B?
Hepatitis B virus hepatitis B virus (HBV) damage, a double-stranded DNA virus. It may appear as an asymptomatic, acute,
chronic, or thunderbolt infection. Acute infection is often characterized by jaundice, nausea and vomiting, joint pains or rashes, often associated with marked increases in liver function tests. Chronic infection is typically asymptomatic and can only be detected by blood tests until it causes late complications such as cirrhosis, portal hypertension or hepatocellular carcinoma. Thunderburn infection with hepatitis B virus is defined as the patient's worsening of hepatic encephalopathy within 8 weeks of onset of the disease.
The virus is transmitted by contact with blood or body fluids of an infected individual. The incubation period is almost 2 to 6 months. Acute infection usually resolves in less than 6 months; when the hepatitis B virus antigen does not disappear from the blood within 6 months, chronic hepatitis is thought to have developed. Every year, in the USA alone, about 300,000 people are infected with hepatitis B. Worldwide, chronic hepatitis affects about 300 million people.
